From Benzoate to cis-1,6-Dihydroxy-2,4-cyclohexadiene-1-carboxylic acid

Graphic of the reaction.

Medline reference
Harayama S, Rekik M, Bairoch A, Neidle EL, Ornston LN. J Bacteriol (1991) 173(23): 7540-8.

Search Medline titles for benzoate 1,2-dioxygenase.
11 citations on June 22, 2012. 
                         Benzoate                          
                             |
                             |  NADH + O2 + H+
                    benzoate | /
             1,2-dioxygenase |/
                  1.14.12.10 | Search GenBank, 17 hits on Apr. 03, 2012
                       Kyoto |\
                      ExPASy | \
                             |  NAD+
                             v
  cis-1,6-Dihydroxy-2,4-cyclohexadiene-1-carboxylic acid
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-carboxy-2-unsubstituted Aromatic -----> 1-Carboxy-1,2-dihydroxy-2-hydroaromatic (bt0368)
[Benzoate] [BBD Main Menu]

Page Author(s): Yuemo Zeng
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0245.
It was generated on April 23, 2024 at 4:23:51 AM CDT. 

© 2024, EAWAG.