From 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate to cis-2-Hydroxypenta-2,4-dienoate and 4-Chlorobenzoate

Graphic of the reaction.

Medline reference
Ahmad D, Fraser J, Sylvestre M, Larose A, Khan A, Bergeron J, Juteau JM, Sondossi M. Gene (1995) 156(1): 69-74.

Search Medline for 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate.
34 citations on June 05, 2012. 
                  2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate                  
                                            |
                                            |  H2O
  2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate | /
                                  hydrolase |/
                                    3.7.1.8 | Search GenBank, 213 hits on Apr. 03, 2012
                                      Kyoto |\
                                     ExPASy | \
                                            |  H+
                                            v
                   cis-2-Hydroxypenta-2,4-dienoate + 4-Chlorobenzoate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-Aldo/keto-2,4-diene-5-ol -----> Carboxylate + 1-ene-4-one (bt0040)
[4-Chlorobiphenyl] [BBD Main Menu]

Page Author(s): Shou-Lin Chang and Dong Jun Oh
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0136.
It was generated on April 20, 2024 at 2:32:38 AM CDT. 

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